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Clinically Diagnosing, Managing & Treating Lipedema In Singapore

Updated on Oct 28, 2026

Lipedema is diagnosed clinically: there is no single scan or blood test for it. A doctor combines your detailed medical history with a physical examination (visual inspection, palpation and the Stemmer sign test) to identify this painful fat disorder. Lipedema, also called lipoedema, adiposis dolorosa or painful fat, is estimated to affect about 11% of adult women worldwide [1], and it is frequently misdiagnosed.

Key takeaways

  • No specific scan or blood test diagnoses lipedema; diagnosis is clinical.
  • Key signs: pain or tenderness, easy bruising, negative Stemmer’s sign, edema and psychological impact [4, 5, 6, 7, 8, 9, 10, 11, 12].
  • A negative Stemmer’s sign points to lipedema; a positive sign may indicate co-existing lymphedema.
  • Imaging (ultrasound or MRI) is used to rule out similar conditions, not to confirm lipedema.
  • Self-checks and the “pinch test” raise awareness but are not diagnostic.
  • It may be more common in Asian women, including in Singapore, than previously understood [2, 3].


What is lipedema?

Lipedema is a chronic medical condition estimated to affect about 11% of adult women worldwide [1]. It is characterised by a symmetrical buildup of painful, disproportionate fat, typically in the legs and arms. It is more than a cosmetic concern: it affects mobility and quality of life.

It is also known as lipoedema, adiposis dolorosa or painful fat.

Is lipedema becoming more recognised in Singapore?

Yes. Lipedema has historically been under-recognised in Asian populations, which has made prevalence studies difficult. Recent clinical publications and case studies show a growing focus on lipedema in Asia [2, 3]. This suggests it may be more common among Asian women, including in Singapore, than previously understood.

Amaris B. Clinic has seen a significant and rising number of patients consulting medical director Dr Ivan Puah for lipedema assessment and management.

Worldwide diagnostic criteria for lipedema (Lipedema Foundation)

The Lipedema Foundation reviewed 9 published diagnostic criteria from 1940 to 2021. The symptoms studied were:


Category Features studied
Fat and tissue Bilateral, symmetrical enlargement of the limbs; disproportionate distribution between upper and lower body; altered tissue texture (thickening, nodules); distal fat tendrils at the knee; cuffing or ring fold at the ankle or wrist; no or limited weight loss in affected tissue
Pain and sensation Pain or tenderness to touch; heavy feeling in the legs or extremities; fatigue in the extremities
Skin and vessels Altered skin appearance or temperature; decreased skin elasticity; telangiectasia; easy bruising
Swelling Edema (pitting or non-pitting); no reduction in volume or pain when the limb is elevated; negative Stemmer’s sign
Movement Abnormal gait and limited mobility (flat feet, knock-knees); hypermobility; muscle weakness
Other Family history; psychological involvement

The 5 symptoms all 9 studies agreed on [4, 5, 6, 7, 8, 9, 10, 11, 12]

  1. Pain or tenderness to touch: Discomfort or pain in the affected fat is a frequent hallmark.
  2. Easy bruising: Patients often bruise easily in the affected areas.
  3. Negative Stemmer’s sign: Pinching a skin fold at the base of the second toe or finger helps tell lipedema from lymphedema.
  4. Edema (pitting or non-pitting): Mild swelling may appear, especially as the day goes on.
  5. Psychological involvement: The chronic nature of lipedema often affects self-esteem and mental wellbeing.


How is lipedema diagnosed in Singapore?

At Amaris B. Clinic, diagnosis uses four steps:

  1. Visual inspection: The doctor looks for symmetrical fat enlargement in the limbs, a disproportionate body shape (for example, a smaller upper body than lower body) and skin changes such as coolness or visible telangiectasia (spider veins).
  2. Palpation: Affected tissue may feel soft and nodular (like peas or rice under the skin) or firm and fibrotic, and is often tender.
  3. Stemmer sign test: A key differential tool. If you can pinch the skin (negative sign), it suggests lipedema. A positive sign may indicate co-existing lymphedema.
  4. Detailed medical history: Personal and family history, symptom onset (often around puberty, pregnancy or other hormonal shifts), mobility issues, response to diet and exercise, and the impact on daily life.

Do I need a scan or blood test to diagnose lipedema?

No. Currently no specific scan or blood test diagnoses lipedema.

  • Blood tests are typically done before any surgery to ensure patient safety.
  • Imaging (ultrasound or MRI) may be used selectively to rule out conditions with similar presentations, such as lymphedema, chronic venous disease or lipohypertrophy.

If you suspect lipedema, book a consultation with Dr Ivan Puah for a clinical assessment and a tailored management plan.

FAQ

How is lipedema diagnosed?

Clinically, through a detailed history and physical examination (visual inspection, palpation and the Stemmer sign test). No single scan or blood test confirms it.

Can I self-diagnose lipedema?

No. Online checklists and the “pinch test” can raise awareness but are not diagnostic tools. Lipedema shares symptoms with other conditions, so a definitive diagnosis needs a clinical assessment by an experienced doctor.

Can lipedema be misdiagnosed?

Yes. It is often mistaken for simple obesity or lymphedema, or dismissed entirely. See a doctor knowledgeable about the condition for an accurate diagnosis and appropriate care plan.

How common is lipedema?

It is estimated to affect about 11% of adult women worldwide [1]. It is thought to be under-recognised in Asian populations [2, 3].

What is the difference between lipedema and lymphedema?

The Stemmer sign helps tell them apart. A negative sign suggests lipedema; a positive sign may indicate lymphedema, which can co-exist.

Do I need to bring a support person to my consultation?

It can help. Lipedema is painful and affects confidence and mobility, so a friend or family member can give moral support and help you remember what was discussed.

What questions should I ask my lipedema doctor?

A good doctor answers patiently, clearly and transparently. Ask:

  • What stage or type of lipedema do I have?
  • Am I a suitable candidate for surgery, and what are the realistic long-term outcomes?
  • What is your specific experience in treating lipedema?
  • What does recovery involve?
  • What are the costs, and is the procedure eligible for MediSave claims?

What red flags should I watch for in a consultation?

Be cautious of any practitioner who says “lipedema is just obesity,” recommends only weight loss as the cure, or calls it a social media trend or internet disease. A qualified doctor takes your symptoms seriously and gives a comprehensive assessment and tailored management options.


Reference

[1] Buck DW 2nd, Herbst KL. Lipedema: A Relatively Common Disease with Extremely Common Misconceptions. Plast Reconstr Surg Glob Open. 2016 Sep 28;4(9):e1043. doi: 10.1097/GOX.0000000000001043. PMID: 27757353; PMCID: PMC5055019.

[2] Eakin, G. S., & Peterson, S. (2023). Lipedema: A current understanding of its pathology and natural history, version 1, May 2023.

[3] Kruppa P, Crescenzi R, Faerber G, Forner-Cordero I, Cornely M, Shayan R, Karnezis T, Simarro JL, de Souza PF, Herbst KL, Ghods M, Michelini S. Lipedema World Alliance Delphi Consensus-Based Position Paper on the Definition and Management of Lipedema: Results from the 2023 Lipedema World Congress in Potsdam. Nat Commun. 2026 Jan 10;17(1):427. doi: 10.1038/s41467-025-68232-z. PMID: 41519859; PMCID: PMC12796449.

[4] Allen E, Hines E. Lipedema of the legs: a syndrome characterisedcharacterised by fat legs and orthostatic oedema. In: Proc Staff Meet Mayo Clin. Vol 15. ; 1940:184-187.

[5] WOLD LE, HINES EAJ, ALLEN EV. Lipedema of the legs; a syndrome characterisedcharacterised by fat legs and edema. Ann Intern Med. 1951;34(5):1243-1250. doi:10.7326/0003-4819-34-5-1243

[6] Buck DW 2nd, Herbst KL. Lipedema: A Relatively Common Disease with Extremely Common Misconceptions. Plast Reconstr Surg Glob Open. 2016;4(9):e1043. doi:10.1097/GOX.0000000000001043

[7] Reich-Schupke S, Schmeller W, Brauer WJ, et al. S1 guidelines: Lipedema. J Dtsch Dermatol Ges. 2017;15(7):758-767. doi:10.1111/ddg.13036

[8] Halk AB, Damstra RJ. First Dutch guidelines on lipedema using the International Classification of Functioning, disability and Health. Phlebology. 2017;32(3):152-159. doi:10.1177/0268355516639421

[9] Wounds UK. Best Practice Guidelines: The Management of Lipedema. Wounds UK; 2017. Accessed October 21, 2020. https://www.lipedema.co.uk/wp-content/uploads/2017/05/WUK_Lipedema-BPS_Web.pdf

[10] ALCOLEA J, ALONSO ÁB, ARROYO BA, et al. Documento de Consenso Lipedema: Consensus document on Lipedema. Published online in 2018.

[11] Bertsch, Tobias, Erbacher, Gabriele. JWC International Consensus Document: Lipedema: a paradigm shift. Journal of Wound Care. 2020;29(11).

[12] Herbst KL, Kahn LA, Iker E, et al. Standard of care for lipedema in the United States. Phlebology. Published online May 28, 2021:02683555211015887. doi:10.1177/02683555211015887

[13] Donahue PMC, Crescenzi R, Petersen KJ, Garza M, Patel N, Lee C, Chen SC, Donahue MJ. Physical Therapy in Women with Early Stage Lipedema: Potential Impact of Multimodal Manual Therapy, Compression, Exercise, and Education Interventions. Lymphat Res Biol. 2022 Aug;20(4):382-390. doi: 10.1089/lrb.2021.0039. Epub 2021 November 8. PMID: 34748408; PMCID: PMC9422785.

[14] https://lipedema.net/compression-garments-therapy-for-lipedema/



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